BioMaxis Implementation Guide
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: HMIS AEFI Reaction Type - JSON Representation

Active as of 2026-02-04

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{
  "resourceType" : "CodeSystem",
  "id" : "hmis-aefi-reaction-type",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem hmis-aefi-reaction-type</b></p><a name=\"hmis-aefi-reaction-type\"> </a><a name=\"hchmis-aefi-reaction-type\"> </a><p>This case-sensitive code system <code>http://biomaxis.com/fhir/CodeSystem/hmis-aefi-reaction-type</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td><td><b>ne</b></td></tr><tr><td style=\"white-space:nowrap\">local-pain<a name=\"hmis-aefi-reaction-type-local-pain\"> </a></td><td>Local Pain</td><td>Pain at the injection site</td><td>सुई लगाएको ठाउँमा दुखाइ</td></tr><tr><td style=\"white-space:nowrap\">local-swelling<a name=\"hmis-aefi-reaction-type-local-swelling\"> </a></td><td>Local Swelling</td><td>Swelling at the injection site</td><td>सुई लगाएको ठाउँमा सुन्निने</td></tr><tr><td style=\"white-space:nowrap\">local-redness<a name=\"hmis-aefi-reaction-type-local-redness\"> </a></td><td>Local Redness</td><td>Redness or erythema at the injection site</td><td>सुई लगाएको ठाउँमा रातो हुने</td></tr><tr><td style=\"white-space:nowrap\">abscess<a name=\"hmis-aefi-reaction-type-abscess\"> </a></td><td>Injection Site Abscess</td><td>Abscess formation at the injection site (sterile or septic)</td><td>सुई लगाएको ठाउँमा फोडा</td></tr><tr><td style=\"white-space:nowrap\">cellulitis<a name=\"hmis-aefi-reaction-type-cellulitis\"> </a></td><td>Cellulitis</td><td>Spreading inflammation of the skin and subcutaneous tissue at injection site</td><td>सेलुलाइटिस</td></tr><tr><td style=\"white-space:nowrap\">lymphadenitis<a name=\"hmis-aefi-reaction-type-lymphadenitis\"> </a></td><td>Lymphadenitis</td><td>Inflammation of lymph nodes, particularly BCG lymphadenitis</td><td>लिम्फ नोड सुन्निने</td></tr><tr><td style=\"white-space:nowrap\">fever<a name=\"hmis-aefi-reaction-type-fever\"> </a></td><td>Fever</td><td>Elevated body temperature following immunization</td><td>ज्वरो</td></tr><tr><td style=\"white-space:nowrap\">rash<a name=\"hmis-aefi-reaction-type-rash\"> </a></td><td>Rash</td><td>Skin rash or urticaria following immunization</td><td>छालामा दाना/लटरम्मे</td></tr><tr><td style=\"white-space:nowrap\">irritability<a name=\"hmis-aefi-reaction-type-irritability\"> </a></td><td>Irritability</td><td>Excessive crying or irritability in infants</td><td>चिडचिडापन</td></tr><tr><td style=\"white-space:nowrap\">drowsiness<a name=\"hmis-aefi-reaction-type-drowsiness\"> </a></td><td>Drowsiness</td><td>Excessive sleepiness or lethargy following immunization</td><td>सुस्तता</td></tr><tr><td style=\"white-space:nowrap\">loss-of-appetite<a name=\"hmis-aefi-reaction-type-loss-of-appetite\"> </a></td><td>Loss of Appetite</td><td>Decreased appetite or refusal to feed</td><td>खान नखोज्ने</td></tr><tr><td style=\"white-space:nowrap\">vomiting<a name=\"hmis-aefi-reaction-type-vomiting\"> </a></td><td>Vomiting</td><td>Vomiting following immunization</td><td>बान्ता</td></tr><tr><td style=\"white-space:nowrap\">diarrhea<a name=\"hmis-aefi-reaction-type-diarrhea\"> </a></td><td>Diarrhea</td><td>Diarrhea following immunization (particularly with rotavirus vaccine)</td><td>झाडा</td></tr><tr><td style=\"white-space:nowrap\">anaphylaxis<a name=\"hmis-aefi-reaction-type-anaphylaxis\"> </a></td><td>Anaphylaxis</td><td>Severe allergic reaction with rapid onset involving multiple body systems</td><td>एनाफिलेक्सिस</td></tr><tr><td style=\"white-space:nowrap\">seizure<a name=\"hmis-aefi-reaction-type-seizure\"> </a></td><td>Seizure/Convulsion</td><td>Convulsions or seizures following immunization (febrile or afebrile)</td><td>खिचौटी/झट्का</td></tr><tr><td style=\"white-space:nowrap\">hypotonic-hyporesponsive<a name=\"hmis-aefi-reaction-type-hypotonic-hyporesponsive\"> </a></td><td>Hypotonic-Hyporesponsive Episode</td><td>Episode of sudden reduced muscle tone, reduced responsiveness, and pallor or cyanosis</td><td>हाइपोटोनिक-हाइपोरेस्पोन्सिभ</td></tr><tr><td style=\"white-space:nowrap\">encephalopathy<a name=\"hmis-aefi-reaction-type-encephalopathy\"> </a></td><td>Encephalopathy</td><td>Acute onset of major illness characterized by altered consciousness, seizures, or focal neurological signs</td><td>इन्सेफालोप्याथी</td></tr><tr><td style=\"white-space:nowrap\">intussusception<a name=\"hmis-aefi-reaction-type-intussusception\"> </a></td><td>Intussusception</td><td>Bowel obstruction where part of intestine folds into itself (associated with rotavirus vaccine)</td><td>इन्टससेप्सन (आन्द्रा भित्र पस्ने)</td></tr><tr><td style=\"white-space:nowrap\">thrombocytopenia<a name=\"hmis-aefi-reaction-type-thrombocytopenia\"> </a></td><td>Thrombocytopenia</td><td>Low platelet count following immunization</td><td>थ्रोम्बोसाइटोपेनिया</td></tr><tr><td style=\"white-space:nowrap\">guillain-barre<a name=\"hmis-aefi-reaction-type-guillain-barre\"> </a></td><td>Guillain-Barré Syndrome</td><td>Acute inflammatory demyelinating polyneuropathy</td><td>गुलिएन-बारे सिन्ड्रोम</td></tr><tr><td style=\"white-space:nowrap\">bcg-osteitis<a name=\"hmis-aefi-reaction-type-bcg-osteitis\"> </a></td><td>BCG Osteitis</td><td>Bone infection following BCG vaccination</td><td>बीसीजी हड्डी संक्रमण</td></tr><tr><td style=\"white-space:nowrap\">disseminated-bcg<a name=\"hmis-aefi-reaction-type-disseminated-bcg\"> </a></td><td>Disseminated BCG Infection</td><td>Widespread BCG infection in immunocompromised individuals</td><td>फैलिएको बीसीजी संक्रमण</td></tr><tr><td style=\"white-space:nowrap\">toxic-shock<a name=\"hmis-aefi-reaction-type-toxic-shock\"> </a></td><td>Toxic Shock Syndrome</td><td>Acute systemic illness with fever, hypotension, and multi-organ involvement</td><td>टक्सिक शक सिन्ड्रोम</td></tr><tr><td style=\"white-space:nowrap\">sepsis<a name=\"hmis-aefi-reaction-type-sepsis\"> </a></td><td>Sepsis</td><td>Systemic infection following immunization</td><td>सेप्सिस (रक्त संक्रमण)</td></tr><tr><td style=\"white-space:nowrap\">death<a name=\"hmis-aefi-reaction-type-death\"> </a></td><td>Death</td><td>Death following immunization (any cause)</td><td>मृत्यु</td></tr><tr><td style=\"white-space:nowrap\">other<a name=\"hmis-aefi-reaction-type-other\"> </a></td><td>Other Reaction</td><td>Other adverse reaction not specified above</td><td>अन्य प्रतिक्रिया</td></tr></table></div>"
  },
  "url" : "http://biomaxis.com/fhir/CodeSystem/hmis-aefi-reaction-type",
  "version" : "0.0.0-semantic-release",
  "name" : "HMISAEFIReactionType",
  "title" : "HMIS AEFI Reaction Type",
  "status" : "active",
  "experimental" : false,
  "date" : "2026-02-04T09:30:33+00:00",
  "publisher" : "BioMaxis Pvt. Ltd.",
  "contact" : [
    {
      "name" : "BioMaxis Pvt. Ltd.",
      "telecom" : [
        {
          "system" : "url",
          "value" : "http://biomaxis.com"
        }
      ]
    }
  ],
  "description" : "Standardized codes for types of Adverse Events Following Immunization (AEFI) reactions used in Nepal's National Immunization Program based on HMIS 2.2.",
  "caseSensitive" : true,
  "content" : "complete",
  "count" : 26,
  "concept" : [
    {
      "code" : "local-pain",
      "display" : "Local Pain",
      "definition" : "Pain at the injection site",
      "designation" : [
        {
          "language" : "ne",
          "value" : "सुई लगाएको ठाउँमा दुखाइ"
        }
      ]
    },
    {
      "code" : "local-swelling",
      "display" : "Local Swelling",
      "definition" : "Swelling at the injection site",
      "designation" : [
        {
          "language" : "ne",
          "value" : "सुई लगाएको ठाउँमा सुन्निने"
        }
      ]
    },
    {
      "code" : "local-redness",
      "display" : "Local Redness",
      "definition" : "Redness or erythema at the injection site",
      "designation" : [
        {
          "language" : "ne",
          "value" : "सुई लगाएको ठाउँमा रातो हुने"
        }
      ]
    },
    {
      "code" : "abscess",
      "display" : "Injection Site Abscess",
      "definition" : "Abscess formation at the injection site (sterile or septic)",
      "designation" : [
        {
          "language" : "ne",
          "value" : "सुई लगाएको ठाउँमा फोडा"
        }
      ]
    },
    {
      "code" : "cellulitis",
      "display" : "Cellulitis",
      "definition" : "Spreading inflammation of the skin and subcutaneous tissue at injection site",
      "designation" : [
        {
          "language" : "ne",
          "value" : "सेलुलाइटिस"
        }
      ]
    },
    {
      "code" : "lymphadenitis",
      "display" : "Lymphadenitis",
      "definition" : "Inflammation of lymph nodes, particularly BCG lymphadenitis",
      "designation" : [
        {
          "language" : "ne",
          "value" : "लिम्फ नोड सुन्निने"
        }
      ]
    },
    {
      "code" : "fever",
      "display" : "Fever",
      "definition" : "Elevated body temperature following immunization",
      "designation" : [
        {
          "language" : "ne",
          "value" : "ज्वरो"
        }
      ]
    },
    {
      "code" : "rash",
      "display" : "Rash",
      "definition" : "Skin rash or urticaria following immunization",
      "designation" : [
        {
          "language" : "ne",
          "value" : "छालामा दाना/लटरम्मे"
        }
      ]
    },
    {
      "code" : "irritability",
      "display" : "Irritability",
      "definition" : "Excessive crying or irritability in infants",
      "designation" : [
        {
          "language" : "ne",
          "value" : "चिडचिडापन"
        }
      ]
    },
    {
      "code" : "drowsiness",
      "display" : "Drowsiness",
      "definition" : "Excessive sleepiness or lethargy following immunization",
      "designation" : [
        {
          "language" : "ne",
          "value" : "सुस्तता"
        }
      ]
    },
    {
      "code" : "loss-of-appetite",
      "display" : "Loss of Appetite",
      "definition" : "Decreased appetite or refusal to feed",
      "designation" : [
        {
          "language" : "ne",
          "value" : "खान नखोज्ने"
        }
      ]
    },
    {
      "code" : "vomiting",
      "display" : "Vomiting",
      "definition" : "Vomiting following immunization",
      "designation" : [
        {
          "language" : "ne",
          "value" : "बान्ता"
        }
      ]
    },
    {
      "code" : "diarrhea",
      "display" : "Diarrhea",
      "definition" : "Diarrhea following immunization (particularly with rotavirus vaccine)",
      "designation" : [
        {
          "language" : "ne",
          "value" : "झाडा"
        }
      ]
    },
    {
      "code" : "anaphylaxis",
      "display" : "Anaphylaxis",
      "definition" : "Severe allergic reaction with rapid onset involving multiple body systems",
      "designation" : [
        {
          "language" : "ne",
          "value" : "एनाफिलेक्सिस"
        }
      ]
    },
    {
      "code" : "seizure",
      "display" : "Seizure/Convulsion",
      "definition" : "Convulsions or seizures following immunization (febrile or afebrile)",
      "designation" : [
        {
          "language" : "ne",
          "value" : "खिचौटी/झट्का"
        }
      ]
    },
    {
      "code" : "hypotonic-hyporesponsive",
      "display" : "Hypotonic-Hyporesponsive Episode",
      "definition" : "Episode of sudden reduced muscle tone, reduced responsiveness, and pallor or cyanosis",
      "designation" : [
        {
          "language" : "ne",
          "value" : "हाइपोटोनिक-हाइपोरेस्पोन्सिभ"
        }
      ]
    },
    {
      "code" : "encephalopathy",
      "display" : "Encephalopathy",
      "definition" : "Acute onset of major illness characterized by altered consciousness, seizures, or focal neurological signs",
      "designation" : [
        {
          "language" : "ne",
          "value" : "इन्सेफालोप्याथी"
        }
      ]
    },
    {
      "code" : "intussusception",
      "display" : "Intussusception",
      "definition" : "Bowel obstruction where part of intestine folds into itself (associated with rotavirus vaccine)",
      "designation" : [
        {
          "language" : "ne",
          "value" : "इन्टससेप्सन (आन्द्रा भित्र पस्ने)"
        }
      ]
    },
    {
      "code" : "thrombocytopenia",
      "display" : "Thrombocytopenia",
      "definition" : "Low platelet count following immunization",
      "designation" : [
        {
          "language" : "ne",
          "value" : "थ्रोम्बोसाइटोपेनिया"
        }
      ]
    },
    {
      "code" : "guillain-barre",
      "display" : "Guillain-Barré Syndrome",
      "definition" : "Acute inflammatory demyelinating polyneuropathy",
      "designation" : [
        {
          "language" : "ne",
          "value" : "गुलिएन-बारे सिन्ड्रोम"
        }
      ]
    },
    {
      "code" : "bcg-osteitis",
      "display" : "BCG Osteitis",
      "definition" : "Bone infection following BCG vaccination",
      "designation" : [
        {
          "language" : "ne",
          "value" : "बीसीजी हड्डी संक्रमण"
        }
      ]
    },
    {
      "code" : "disseminated-bcg",
      "display" : "Disseminated BCG Infection",
      "definition" : "Widespread BCG infection in immunocompromised individuals",
      "designation" : [
        {
          "language" : "ne",
          "value" : "फैलिएको बीसीजी संक्रमण"
        }
      ]
    },
    {
      "code" : "toxic-shock",
      "display" : "Toxic Shock Syndrome",
      "definition" : "Acute systemic illness with fever, hypotension, and multi-organ involvement",
      "designation" : [
        {
          "language" : "ne",
          "value" : "टक्सिक शक सिन्ड्रोम"
        }
      ]
    },
    {
      "code" : "sepsis",
      "display" : "Sepsis",
      "definition" : "Systemic infection following immunization",
      "designation" : [
        {
          "language" : "ne",
          "value" : "सेप्सिस (रक्त संक्रमण)"
        }
      ]
    },
    {
      "code" : "death",
      "display" : "Death",
      "definition" : "Death following immunization (any cause)",
      "designation" : [
        {
          "language" : "ne",
          "value" : "मृत्यु"
        }
      ]
    },
    {
      "code" : "other",
      "display" : "Other Reaction",
      "definition" : "Other adverse reaction not specified above",
      "designation" : [
        {
          "language" : "ne",
          "value" : "अन्य प्रतिक्रिया"
        }
      ]
    }
  ]
}